Education
Postdoctoral Scholar, Marine Biomedicine and Environmental Sciences Program, Department of Obstetrics and Gynecology, Medical University of South Carolina & Hollings Marine Laboratory
Ph.D. in Cellular Biology, University of Georgia
B.S. in Biology, University of North Carolina—Wilmington
Research Interests
- Molecular Ecology
- Organismal Ecology
- Human Ecology
- Aquatic Ecology
- Radiation Ecology
- Disease Ecology
We are broadly interested in questions of environmental health. How does the environment experienced by a developing embryo influence health outcomes later in life? Are these interactions adaptive or disruptive? What are the mechanisms? What are the consequences at the individual, population, and ecosystem levels? We are also pursuing projects that examine how environmental quality influences fundamental processes of biological aging. What are the mechanisms by which factors like exposures to contaminants influence aging trajectories? Much of our active research is focused on addressing these questions in environmental models and humans. Check out our website which is updated more frequently.
Selected Publications
McCoy JA, Bangma JT, Reiner JL, Bowden JA, Schnorr J, Slowey M, O’Leary T, Guillette LJ, Parrott BB. Associations between perfluorinated alkyl acids in blood and ovarian follicular fluid and ovarian function in women undergoing assisted reproductive treatment. 2017 Science of the Total Environment (DOI: https://doi.org/10.1016/j.scitotenv.2017.06.137)
McCoy JA, Hamlin HJ, Thayer L, Guillette LJ Jr, Parrott BB. The influence of thermal signals during embryonic development on intrasexual and sexually dimorphic gene expression and circulating steroid hormones in American alligator hatchlings (Alligator mississippiensis). 2016. General and Comparative Endocrinology (DOI: http://dx.doi.org/10.1016/j.ygcen.2016.04.011)
Guillette LJ Jr, Parrott BB, Nilsson E, Haque MM, Skinner MK. Epigenetic alterations in alligators from environmentally contaminated lakes. 2016. [In Press at General and Comparative Endocrinology, draft available upon request]
Doheny BM, Kohno S, Parrott BB, Guillette LJ Jr. In ovo treatment with an estrogen receptor alpha selective agonist causes precocious development of the female reproductive tract of the American alligator (Alligator mississippiensis). 2016. General and Comparative Endocrinology (DOI: http://dx.doi.org/10.1016/j.ygcen.2016.02.026).
Yatsu R, Miyagawa S, Kohno S, Parrott BB, Yamaguchi K, Miyakawa H, Shigenobu S, Guillette LJ, Iguchi T. RNA-seq analysis of the gonadal transcriptome during Alligator mississippiensis temperature-dependent sex determination and differentiation. 2016. BMC Genomics 17:77 (DOI: 10.1186/s12864-016-2396-9)